The 30-share Sensex ended down by 59 points at 27,027 and the 50-share Nifty slipped 7 points at 8,087.
But the 30-share Sensex rose by 141.52 points, or 0.41 per cent, to close at 34,297.47. The broader NSE Nifty gained 44.60- points, or 0.42 per cent, to end at 10,545.50 after touching a high of 10,618.10.
The NSE Nifty settled the day 38.85 points or 0.37 per cent lower at 10,500.90 after shuttling between 10,590.55 and 10,456.65, intra-day.
Natco Pharma, Wockhardt and Marksans have rallied between 50 and 70 per cent in the year till date.
The breakdown of talks between Greece and its international creditors raised fears of Greece's exit from the euro zone.
Pharma shares extended losses after the government's ban on combination drugs.
The 50-share NSE Nifty shed some ground to settle at 8,699.40 points, up 40.30 points, or 0.47 per cent
HDFC twins, Axis Bank, ICICI Bank and SBI from the financial space gained between 1-2.7%.
Surprisingly, RIL scrip also fell by 2.73 per cent to 1,029.15, becoming the second biggest loser in the index
Early last year, the company had said it aimed to reduce its debt, which stood over Rs 21,000 crore then, to Rs 10,000-11,000 crore (Rs 100-110 billion) through the sale of non-core assets and improved cash flows.
The 50-issue NSE Nifty too cracked the 10,200-mark and hit a low of 10,108.55 before finishing 104.75 points, or 1.02 per cent down at 10,121.80.
Stock market investors on Friday became richer by over Rs 1 lakh crore as the share market rose and the benchmark Sensex galloped to a new closing high enthused by the clear win of Narendra Modi-led BJP in Lok Sabha polls.
Sensex witnessed the biggest single day gain since May 2009 in absolute terms.
The benchmark Nifty rallied 1,000 points or 17% from 7,000 in 78 trading sessions since May 12, till date to surpass the 8,000 mark.
In the metal pack, Tata Steel was up 3.7% while Vedanta was up 1.8% .
The 30-share Sensex and the 50-share Nifty ended flat at the mark of 29,008 and 8,767 respectively.
The NSE Nifty also moved up by 12 points to 8,648.35.
Construction major L&T was the biggest gainer among the Sensex components, spurting 2.30 per cent, after the company said its board has approved a Rs 9,000-crore share buyback plan.
Investors have kept their eyes on US-China trade talks and are optimistic about a positive outcome.
Market breadth was weak with 1239 losers and 1078 gainers on the BSE.
BSE Mid-cap index ended lower by over 2.5% and BSE Small-cap index tumbled over 3%.
Index heavyweights were the top losers along with bank shares.
The BSE Sensex zoomed 318 points to end at 33,351.57, while the broader Nifty spurted 88 points to 10,242.65.
The S&P BSE Sensex plunged 301 points to close at 25,490 and the Nifty50 fell 86 points to end at 7,815.
BSE Metal and Capital Goods indices plunged over 2% followed by counters like Consumer Durables, Auto, Banks and Realty, all falling down between 1-2%.
IT majors along with metal names Sesa Goa and Hindalco buck trend.
The 30-share Sensex ended 53 points higher at 28,439 and the 50-share Nifty closed 18 points higher at 8,494.
ICICI Bank, ONGC and Tata Motors contribute to nearly 50% gain seen on the Nifty.
Most of the session's gains for both the indices were wiped out as investors rushed to book profits ahead of F&O expiry on Thursday and also due to concerns over stretched valuations.
The 30-share Sensex lost 54 points at end at 27,086 and 50-share Nifty shed 19 points to close at 8,096.
The broad-based NSE Nifty rose 52.80 points, or 0.50 per cent, to end at 10,530.70
ITC, Sun Pharma, Cipla and Tata Steel were top gainers on BSE Sensex
Broader market outperformed the headline indices with BSE Midcap and Smallcap finishing the day 1.22%, and 1.54% higher, respectively
The NSE 50-share Nifty spurted 97.25 points, or 0.92 per cent, to 10,715.50
Broad-based buying aided sentiment and the market registers record turnover at Rs 6.86 lakh crore
A steep decline in the Asian equities after crude oil fell to its lowest since September 2003 dented sentiments.
Sensex closed over 118 points down on Thursday.
The sentiment-driven rally also got support from stock specific earning results and Finance Minister Arun Jaitley's statement that the Centre will step up reforms to attract more investment and fill up infrastructure deficit.
The 30-share Sensex ended down 261 points at 27,177 and the 50-share Nifty ended down 91 points at 8,214.
Custodian banks are selling dollars for their foreign fund clients.